I am a faculty member at the University of Chicago. I am the Director of the Center for Data Intensive Science; a Senior Fellow and Core Faculty in the Institute for Genomics and Systems Biology (IGSB), a Senior Fellow and Core Faculty in the Computation Institute; and a Professor in the Department of Medicine in the Section of Genetic Medicine.

I am also the Director of the not-for-profit Open Cloud Consortium (OCC), which develops and operates cloud computing infrastructure for the research community, including the Open Science Data Cloud.

My research group at the University of Chicago focuses on bioinformatics, big data, data science, cloud computing and related areas. I am the PI for the Bionimbus Protected Data Cloud, which is an open-source cloud-based computational platform that allows researchers authorized by NIH to compute over human genomic data in a secure and compliant fashion.

I have participated in the development of open source software to transport (UDT), manage (Sector) and analyze (Augustus) big data.